Photograph of Dr. Tippi Cicek MacKenzie

The American Society for Clinical Investigation is proud to present the ASCI Scientific Sessions: a monthly spotlight on distinguished investigators and their contributions to biomedical research. The Scientific Sessions are free and open to all, with a goal to create a space for our community, beyond the ASCI’s annual meeting, to gather and celebrate discovery.

Tippi Cicek MacKenzie, MD, is Professor of Surgery at the University of California, San Francisco, and Director of the Eli and Edythe Broad Institute of Regeneration Medicine. She is a pediatric and fetal surgeon focused on developing better ways to diagnose and treat genetic diseases before birth.Dr. MacKenzie runs a translational research lab examining fetal immunology and maternal-fetal tolerance. She recently co-founded the Center for Maternal-Fetal Precision Medicine, with the aim of accelerating the processes that link basic research to clinical trials to improve maternal, fetal, and neonatal health. Dr. MacKenzie has moved two fetal molecular therapies from the lab to phase 1 clinical trials: in utero hematopoietic stem cell transplantation to treat fetuses with alpha thalassemia and in utero enzyme replacement therapy in fetuses with lysosomal storage disorders.

Dr. MacKenzie’s many honors include the American College of Surgeons’ Jacobson Award for her innovative work and election to the National Academy of Medicine in 2022. Dr. MacKenzie was elected to the American Society for Clinical Investigation in 2021.

This session will be moderated by Valerie Arboleda, MD, PhD, Associate Professor of Pathology and Laboratory Medicine, Human Genetics, and Computational Medicine at the University of California, Los Angeles, David Geffen School of Medicine. Elected to ASCI membership in 2022, Dr. Arboleda serves on the ASCI Physician-Scientist Development Committee.