Alexander Marson, MD, PhD
Decoding and reprogramming T cell circuits with CRISPR
Description
The American Society for Clinical Investigation is proud to present the ASCI Scientific Sessions: a bi-monthly spotlight on distinguished investigators and their contributions to biomedical research. The Scientific Sessions are free and open to all, with a goal to create a space for our community, beyond the ASCI’s annual meeting, to gather and celebrate discovery.
Alexander Marson, MD, PhD, is Director of the Gladstone-UCSF Institute of Genomic Immunology and Professor in the UCSF Department of Medicine, Division of Infectious Diseases. He serves as the Director of the Parker Institute of Cancer Immunotherapy at Gladstone, the scientific director for Human Health at the Innovative Genomics Institute (IGI) and is a Chan Zuckerberg Biohub investigator.
Dr. Marson’s lab aims to understand genetic programs controlling human immune cell function in health and disease, with an emphasis on developing and applying CRISPR genome engineering tools to primary immune cells, especially T cells. Combining genomics and gene editing approaches, the lab assesses the consequences of coding and noncoding genetic variation on immune cell function and autoimmune disease risk and to genetically engineer human immune cells to target cancer, autoimmunity, and infectious diseases.
Dr. Marson is the recipient of many awards and honors, including the NIDA/NIH Avenir Award, and the CRI Lloyd J. Old STAR Award. He was elected to the ASCI in 2019.
This session will be moderated by Jennifer S. Yu, MD, PhD. Dr. Yu, Associate Professor of Radiation Oncology at the Cleveland Clinic, has been recognized for her work to improve therapy for patients with brain tumors, in particular glioblastoma. She serves on the ASCI Diversity, Equity, and Inclusion Committee and was elected to the ASCI in 2020.